In March 2006, Lamborghini unveiled an updated version of its halo car at the Geneva Motor Show: the Murciélago LP 640. The new title incorporated the car’s name, along with an alphanumeric designation which indicated the engine’s orientation (Longitudinale Posteriore), along with the updated power output. With displacement now increased to 6.5 litres, the engine produced 640 PS (471 kW; 631 hp) at 8,000 rpm. The exterior received a noticeable facelift, featuring revised front and rear fascias, and asymmetrical side air intakes, with the left side intake feeding an oil cooler.
A new single outlet exhaust system incorporated into the rear diffuser, modified suspension system, revised programming and upgraded clutch for the 6-speed «e-Gear» automated sequential transmission with launch control rounded out the performance modifications.
Interior seating was also re-configured in order to provide greater headroom, and a new stereo system formed part of the updated dashboard. Optional equipment included Carbon fibre-reinforced Silicon Carbide (C/SiC) ceramic composite brakes, chrome paddle shifters and a glass engine cover. The car’s estimated fuel economy for the 6-speed manual variant is 8 miles per U.S. gallon (29 L/100 km; 9.6 mpg‑imp) in the city and 13 miles per U.S. gallon (18 L/100 km; 16 mpg‑imp) on the highway, making it the least efficient car in 2008 for city and highway driving, according to the EPA. A second generation Murciélago LP 640 was fittingly used in the 2008 movie The Dark Knight.